Combined drug medium with isoniazid and rifampicin for identification of multi-drug resistant Mycobacterium tuberculosis

Nalini, S and Lakshmi, R and Devika, K and Ravikumar, D and Ramachandran, R (2010) Combined drug medium with isoniazid and rifampicin for identification of multi-drug resistant Mycobacterium tuberculosis. Indian Journal of Medical Microbiology, 28 (2). pp. 162-163. ISSN Print: 0255-0857 | Electronic: 1998-3646

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Abstract

A low-cost method of detecting multi-drug resistant Mycobacterium tuberculosis (MDR-TB) with the possibility of quick adoption in a resource limited setting is urgently required. We conducted a study combining isoniazid and rifampicin in a single LJ medium, to detect MDR-TB strains. Combined and individual drug media showed 100% concordance for the detection of MDR-TB and susceptible strains by proportion method. Considering the results, combined isoniazid and rifampicin containing medium could be considered for use in settings where the sole detection of MDR-TB strains is justified.

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
Uncontrolled Keywords:	Mycobacterium tuberculosis, MDR-TB, Isoniazid, Rifampicin, PST
Subjects:	Tuberculosis > Laboratory Research > Bacteriological
Divisions:	Basic Science Research > Bacteriology
Depositing User:	Dr. Rathinasabapati R
Date Deposited:	23 Mar 2022 10:08
Last Modified:	23 Mar 2022 10:08
URI:	http://eprints.nirt.res.in/id/eprint/1041

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