Sundaramurthi, J C and Ramanathan, P and Brindha, S and Subhasree, C R and Prasad, A and Kumaraswamy, V and Hanna, L E (2011) DDTRP: Database of Drug Targets for Resistant Pathogens. Bioinformation, 7 (2). pp. 98-101. ISSN Print 0973-2063 | Online 0973-8894
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Abstract
Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called ‘Database of Drug Targets for Resistant Pathogens’ (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.
Affiliation: | ICMR-National Institute for Research in Tuberculosis |
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Item Type: | Article |
Uncontrolled Keywords: | DDTRP, drug targets, resistant pathogens, database, drug discovery |
Subjects: | Tuberculosis > Operational Research |
Divisions: | Biomedical Informatics |
Depositing User: | Dr. Rathinasabapati R |
Date Deposited: | 22 Jun 2022 05:07 |
Last Modified: | 22 Jun 2022 05:07 |
URI: | http://eprints.nirt.res.in/id/eprint/1118 |
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