Devi, PoornaGanga (2017) Xpert Mtb/Rif Assay for the diagnosis of pulmonary and extra pulmonary tuberculosis in Paediatric Population. IOSR-Journal of Dental and Medical Sciences, 16 (8). pp. 57-58. ISSN Online 2279-0853 | Print 2279-0861
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Abstract
Detecting patients with active Tuberculosis (TB) disease is an important component of tuberculosis control programs, as early diagnosis and treatment of tuberculosis is essential in reducing the morbidity, mortality and the escalating costs associated with advanced disease. We conducted this study to access the usefulness of Gene Xpert MTB/RIF assay technique in the diagnosis of childhood tuberculosis. We retrospectively reviewed the clinical records and rapid diagnostic results of children less than 14 yrs of age with suspected Tuberculosis who visited the pulmonary clinic of Government Rajaji Hospital (GRH), Madurai from January 2017 to June 2017. Various pulmonary and extra pulmonary specimens were collected under aseptic precautions. These Xpert MTB/RIF samples were processed according to the manufacturer’s specifications. A total of 96 consecutive pulmonary and extra pulmonary clinical samples were included. Fifty eight (60.4%) of them were females. Out of 96 samples, 1 (1.1%) tested positive for M.tuberculosis and all were sensitive to Rifampicin.This study shows that GenXpert is useful in the early diagnosis of tuberculosis and that prevalence of Rifampicin resistance is not high in paediatric population
| Affiliation: | ICMR-National Institute for Research in Tuberculosis |
|---|---|
| Item Type: | Article |
| Uncontrolled Keywords: | Gene-Xpert, tuberculosis, children |
| Subjects: | Tuberculosis > Clinical Research |
| Divisions: | Clinical Research |
| Depositing User: | Dr. Rathinasabapati R |
| Date Deposited: | 20 Oct 2022 10:38 |
| Last Modified: | 20 Oct 2022 10:38 |
| URI: | http://eprints.nirt.res.in/id/eprint/1547 |
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