Increased serum levels of anti-filarial (IgA) antibodies in patients with tropical pulmonary eosinophilia

Paranjape, R S and Kumaraswami, V and Prabhakar, R and Narayanan, P R (1985) Increased serum levels of anti-filarial (IgA) antibodies in patients with tropical pulmonary eosinophilia. Lung India, 3 (1). pp. 27-29. ISSN Print: 0970-2113; Online: 0974-598X

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Abstract

Tropical Pulmonary Eosinophilia (TPE) is diagnosed on the basis of high peripheral eosinophilia associated with clinical symptoms and signs. Elevated levels of total and antifilarial immunoglobulins is one of the characteristic features of TPE. Ten clinically diagnosed TPE patients and ten controls were compared for their anti-filarial and anti-ascaris antibody levels of classes IgG, IgM and IgA. While, IgG antibodies exhibited considerable cross reactivity between Ascaris and Filarial antigens, IgM antibodies showed nonspecific binding to filarial antigens. However, IgA antibodies were found to discriminate between TPE and control sera better than IgG and IgM antibodies.

Item Type:	Article
URI:	http://eprints.nirt.res.in/id/eprint/195

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