A systematic review and meta-analysis of circulating serum and plasma microRNAs in TB diagnosis

Gunasekaran, Harinisri and Sampath, Pavithra and Thiruvengadam, Kannan and Malaisamy, Muniyandi and Ramasamy, Rathinasabapati and Ranganathan, Uma Devi and Bethunaickan, Ramalingam (2024) A systematic review and meta-analysis of circulating serum and plasma microRNAs in TB diagnosis. A systematic review and meta-analysis of circulating serum and plasma microRNAs in TB diagnosis, 24(402. pp. 1-12.

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Abstract

Tuberculosis (TB) ranks as the second leading cause of death globally among all infectious diseases. This problem is likely due to the lack of biomarkers to differentiate the heterogeneous spectrum of infection. Therefore, the first step in solving this problem is to identify biomarkers to distinguish the different disease states of an individual and treat them accordingly. Circulating microRNA (miRNA) biomarkers are promising candidates for various diseases. In fact, we are yet to conceptualize how miRNA expression influences and predicts TB disease outcomes. Thus, this systematic review and meta-analysis aimed to assess the diagnostic efficacy of circulating miRNAs in Latent TB (LTB) and Active Pulmonary TB (PTB).

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
Uncontrolled Keywords:	Tuberculosis, microRNA, Biomarker, miR-197, miR-144, TB diagnosis
Subjects:	Tuberculosis > Laboratory Research > Immunological
Divisions:	Basic Science Research > Immunology
Depositing User:	Mrs. N Lakshmi
Date Deposited:	02 May 2024 06:23
Last Modified:	02 May 2024 06:23
URI:	http://eprints.nirt.res.in/id/eprint/2000

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