Tuberculosis and alcohol use; findings from a subnational TB prevalence survey in India

Giridharan, Prathiksha and Ariarathinam, Newtonraj and Thiruvengadam, Kannan and Selvaraju, Sriram (2025) Tuberculosis and alcohol use; findings from a subnational TB prevalence survey in India. Tuberculosis and alcohol use; findings from a subnational TB prevalence survey in India, 0019 (5707).

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Abstract

Population based surveys are crucial in understanding the relation between alcohol usage and tuberculosis epidemiology. Methods: A state-wide population-based large sample size cross-sectional Tuberculosis (TB) survey was conducted in India. Participants from 180 clusters were screened with x-ray and sputum examination. Results: In total 130,932 participants were screened. Among the “alcohol-use” population 115(0.6 %) and among non-alcoholics 129(0.12 %) were diagnosed with microbiologically confirmed pulmonary tuberculosis (MCPTB). The adjusted prevalence ratio (aPR) of MCPTB in the alcohol-use population was 4.2(3.24–5.45). The adjustedPR(aPR) of MCPTB disease in ‘alcohol-use’ population was significantly associated with increasing age, under nutrition and past history of TB. The aPR for age between 31 and 45 years was 2.85(0.9–8.6); 46–60 years was 6.24(2.3–16.8) and >60 years was 7.77(2.7–21.6). For BMI of 18.50–22.99 was 3.2(1.6–6.2), BMI of 16.50–18.49 was 9.9(4.7–21.1) and BMI of <16.50 was 14.0(6.3–31.5)). For past history of TB was 3.76 (2.2–6.5). The number needed to screen to diagnose one participant with MCPTB in the general population was 537 and in ‘alcohol-use’ group was 168. Conclusion: The prevalence of MCPTB in ‘alcohol-use’ individuals is four times higher when compared to nonalcoholic individuals. Increases in age, undernutrition and past history of PTB were highly associated with MCPTB disease among ‘alcohol-use’ participants.

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
Uncontrolled Keywords:	Pulmonary tuberculosis, Alcohol addiction, Alcoholism, Alcohol drinking habits, Alcohol consumption, Alcohol use disorder, Alcohol-related disorders
Subjects:	Tuberculosis > Clinical Research Tuberculosis
Divisions:	Clinical Research
Depositing User:	Mrs. N Lakshmi
Date Deposited:	28 Mar 2025 12:28
Last Modified:	28 Mar 2025 12:28
URI:	http://eprints.nirt.res.in/id/eprint/2028

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