Low-complexity manual nucleic acid amplification tests for pulmonary tuberculosis in children.

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Inbaraj, Leeberk Raja and Sathya Narayanan, Mukesh Kumar and Daniel, Jefferson and Srinivasalu, Vignes Anand and Bhaskar, Adhin and Daniel, Bella Devaleenal and Epsibha, Tephilla and Scandrett, Katie and Rajendran, Priya and Rose, Winsley and Korobitsyn, Alexei and Ismail, Nazir and Takwoingi, Yemisi (2025) Low-complexity manual nucleic acid amplification tests for pulmonary tuberculosis in children. Low-complexity manual nucleic acid amplification tests for pulmonary tuberculosis in children., 6 (CD0158).

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Official URL: https://DOI: 10.1002/14651858.CD015806.pub2

Abstract

Accurate and prompt diagnosis of tuberculosis in children is challenging due to non-specific clinical presentation and the low bacillary load of samples. Low-complexity manual nucleic acid amplification tests (LC-mNAATs) such as loop-mediated isothermal amplification (TB-LAMP) are World Health Organization (WHO)-recommended rapid molecular diagnostic tests. Even in resource-limited settings, they have good diagnostic accuracy in adults.

Affiliation:	ICMR-Natioanl Institute for Research in Tuberculosis
Item Type:	Article
URI:	http://eprints.nirt.res.in/id/eprint/2047

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