Efficacy & safety of high-dose rifampicin in pulmonary tuberculosis: A systematic review & meta-analysis

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Perumal Kannabiran, Bhavani and Arthanari, Jayanthi and Bhaskar, Adhin and Sathya Narayanan, Mukesh Kumar and Inbaraj, Leeberk Raja (2025) Efficacy & safety of high-dose rifampicin in pulmonary tuberculosis: A systematic review & meta-analysis. Efficacy & safety of high-dose rifampicin in pulmonary tuberculosis: A systematic review & meta-analysis, 161 (5).

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Official URL: https://doi: 10.25259/IJMR_1673_2024

Abstract

Evidence suggests that higher doses of rifampicin aid in faster culture conversion, but its effects on unfavourable outcomes are unclear. We aimed to synthesise evidence on the efficacy and safety of high-dose rifampicin (>15 mg/kg) containing anti-tuberculosis regimen compared to a regimen with standard dose of rifampicin in adults with pulmonary tuberculosis.

Affiliation:	ICMR-National Institute for Research in Tubercuosis
Item Type:	Article
URI:	http://eprints.nirt.res.in/id/eprint/2050

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