Impact of Strongyloides stercoralis infection on complementactivation in Type 2 diabetes mellitus: Insights from a clinical and anthelmintic intervention study

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Rajamanickam, A and Dasan, B and Munisankar, S and Nott, S and Menon, P A and Ahamed Shaik, P and Chinnaiyan, P and Nutman, TB and Babu, S. (2024) Impact of Strongyloides stercoralis infection on complementactivation in Type 2 diabetes mellitus: Insights from a clinical and anthelmintic intervention study. Impact of Strongyloides stercoralis infection on complementactivation in Type 2 diabetes mellitus: Insights from a clinical and anthelmintic intervention study, 18(4) (e00120).

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Official URL: https://doi.org/10.1371/journal.pntd.0012048.g002

Abstract

Numerousstudies indicate a potential protective role of helminths in diabetes mellitus (DM) progression. The complement system, vital for host defense, plays a crucial role in tissue homeostasis and immune surveillance. Dysregulated complement activation is implicated in diabetic complications. We aimed to investigate the influence of the helminth, Strongyloides stercoralis (Ss) on complement activation in individuals with type 2 DM (T2D).

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
URI:	http://eprints.nirt.res.in/id/eprint/2153

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