Discovery of a blood-based miRNA signature that can predict onset of active tuberculosis among household contacts of TB patients

Daniel, EA and Thiruvengadam, K. and Chandrasekaran, P. and Hilda, N and Umashankar, P and Prashanthi, P and Selvachithiram, M and Pattabiraman, S and Bhanu, B and Sivaprakasam, A and Paradkar, M. and Kulkarni, V. and Karyakarte, R and Shivakumar, SVBY and Mave, V. and Gupta, A and Hanna, L. E. (2024) Discovery of a blood-based miRNA signature that can predict onset of active tuberculosis among household contacts of TB patients. Discovery of a blood-based miRNA signature that can predict onset of active tuberculosis among household contacts of TB patients, 2 (141534).

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Abstract

Non-sputum based predictive biomarkers capable of identifying individuals with high risk of progression to active tuberculosis (TB) are critical for global TB control. MicroRNAs (miRNAs) are significant regulators involved in TB pathogenesis and hence we aimed to identify a miRNA signature capable of predicting progression to TB disease.

Affiliation: ICMR-National Institute for Research in Tubercuosis
Item Type: Article
URI: http://eprints.nirt.res.in/id/eprint/2183

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