Genotype MTBDRsl Version 2 and Phenotypic Drug Resistance Detection of Mycobacterium tuberculosis for Fluoroquinolones and Aminoglycosides

Radhakrishnan, R and Prabuseenivasan, S and Hannah, S and Vaishanavee, V and Senthildevi, V and Kannadhasan, T and Suchithra, R and Rajendran, P and Chinnaiyan, P and Shanmugam, S (2023) Genotype MTBDRsl Version 2 and Phenotypic Drug Resistance Detection of Mycobacterium tuberculosis for Fluoroquinolones and Aminoglycosides. Genotype MTBDRsl Version 2 and Phenotypic Drug Resistance Detection of Mycobacterium tuberculosis for Fluoroquinolones and Aminoglycosides, 12(3) (299-304).

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Abstract

Information on genotypic with comparison of phenotypic drug sensitivity test of anti‑tuberculosis (TB) has been reported in several studies, which have variable results. The present study aimed to assess the Genotype MTBDRsl version 2.0/Line probe assay (LPA) for the detection of fluoroquinolones (FQ) and aminoglycosides (AMGs) resistance mutations among drug‑resistant Mycobacterium TB (MTB) strains and also to compare the patterns of genotypic mutations of gyrA/B, rrs, and eis with mycobacteria growth indicator tube (MGIT 960).

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
URI:	http://eprints.nirt.res.in/id/eprint/2246

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