Effect of haemoglobin on the growth of mycobacteria and production of siderophores

Raghu, B and Raghupati Sarma, G and Venkatesan, P (1993) Effect of haemoglobin on the growth of mycobacteria and production of siderophores. Indian Journal of Pathology and Microbiology, 36 (4). pp. 376-382. ISSN 0377-4929

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Abstract

Hemoglobin is known to support the growth of several bacterial species. The growth and the production of siderophores by 4 strains of mycobacteria in the presence of hemoglobin was studied in vitro. The findings were compared with those obtained in the presence of equivalent concentrations of iron in the medium. Increase in the concentrations of hemoglobin caused an appreciable increase in the growth of all 4 strains. This was however, accompanied by a significant decrease in the production of both exochelins and mycobactins. It was also observed that hemoglobin supported the growth of all strains as well as that with free iron and the concentrations of both siderophores was significantly higher in the presence of hemoglobin than in that of free iron.

Item Type:	Article
Uncontrolled Keywords:	Hemoglobin; Mycobacterium
Subjects:	Tuberculosis > Laboratory Research > Biochemical
Divisions:	Basic Science Research > Biochemistry
Depositing User:	Dr. Rathinasabapati R
Date Deposited:	20 Sep 2013 10:55
Last Modified:	14 Mar 2016 06:40
URI:	http://eprints.nirt.res.in/id/eprint/345

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