Early clinical, pulmonary function and blood gas studies in victims of Bhopal tragedy

Vijayan, V K and Kuppurao, K V (1993) Early clinical, pulmonary function and blood gas studies in victims of Bhopal tragedy. Biomedicine, 13 (1). pp. 36-42. ISSN 0970 2067

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Abstract

Clinical, Pulmonary function and blood gas studies carricd out in 129 symptomatic toxic gas exposed individuals 1-3 months after exposure had revealed that pulmonary function measurements such as FVC, FEV1 and FMF 25-75% were significantly lower in toxic gas exposed subjects and 57 subjects (44.2%) had ventilatory impairment. The predominant type of ventilatory defect was combined obstruction and restriction. Of these 57 subjects, 5 (9%) had severe respiratory impairment. With increasing severity of exposure, there was a tendency for a higher proportion of subjects to have increasing impairment in pulmonary function and this trend was significant statistically (P<0.001). Isolated small airway disease was present in 9 (7%) subjects. 20.3% of patients with normal physical findings and 19.1% with normal chest roentgenograms had abnormal pulmonary junction. Arterial hypoxemia and ventilatory abnormalities were predominant in severely exposed patients. Further studies are required to identify the subgroup o/patients with Reactive Airways Dysfunction Syndrome. Long term follow-up is essential to categorise the pulmonary syndromes due to toxic gas exposure.

Item Type:	Article
Subjects:	Tuberculosis > Clinical Research
Divisions:	Clinical Research
Depositing User:	Dr. Rathinasabapati R
Date Deposited:	23 Sep 2013 11:01
Last Modified:	14 Mar 2016 07:07
URI:	http://eprints.nirt.res.in/id/eprint/359

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