In vitro activity of ofloxacin and ciprofloxacin against South Indian isolates of M. tuberculosis

Venkataraman, P and Paramasivan, C N and Prabhakar, R (1994) In vitro activity of ofloxacin and ciprofloxacin against South Indian isolates of M. tuberculosis. Indian Journal of Tuberculosis, 41 (2). pp. 87-90. ISSN 0019-5705

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Abstract

Mycobacterium tuberculosis isolates from 104 south Indian patients, including 52 sensitive to Streptomycin (S), Isoniazid, (H) and Rifampicin (R), and 52 resistant to SHR/HR were tested for their in vitro susceptibility to Ciprofloxacin and Ofloxacin on Lowenstein-Jensen medium. The geometric mean for minimal inhibitory concentration (MIC) of Ciprofloxacin was 2.00 mcg/ml for sensitive strains and 2.17 mcg/ml for resistant strains, the overall mean being 2.08 mcg/ml. Considering Ofloxacin, the MICs for the different categories of strains were again similar, there being no difference between sensitive and resistant strains, the geometric means being 2.00 and 2.05 mcg/ml, respectively.

Item Type: Article
Subjects: Tuberculosis > Laboratory Research > Bacteriological
Divisions: Basic Science Research > Bacteriology
Depositing User: Rathinasabapati R
Date Deposited: 24 Sep 2013 09:36
Last Modified: 14 Mar 2016 06:04
URI: http://eprints.nirt.res.in/id/eprint/387

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