Ramu, G and Karthikeyan, S and Balakrishnan, S and Patil, S A and Ramanathan, V D and Desikan, K V (1996) Histological and immunological correlates of suspected leprosy lesions. Indian Journal of Leprosy, 68 (2). pp. 155-159. ISSN 0024-1024
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Abstract
Thirty-two subjects with suspected leprosy lesions were investigated to assess various modalities of sensibility and sweatfunction and these were correlated with immunological and histological parameters. It was found that pain and temperature, mediated by small unmyelinated fibres were impaired in the early lesions. Impairment of sweat function was seen only when one of the modalities of sensibility was also affected Antibodies specific to a protein (35 kDa) antigen and phenolic glycolipid 1 of Mycobacterium leprae were positive in nine and 12 cases respectively, while 15 of the 31 biopsies revealed the presence of mycobacterial antigens in these lesions. The implications of these findings are discussed.
| Item Type: | Article |
|---|---|
| Subjects: | Leprosy |
| Divisions: | Clinical Research |
| Depositing User: | Dr. Rathinasabapati R |
| Date Deposited: | 27 Sep 2013 08:46 |
| Last Modified: | 14 Mar 2016 05:06 |
| URI: | http://eprints.nirt.res.in/id/eprint/417 |
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