Trends in the prevalence and incidence of tuberculosis in South India

Tuberculosis Research Centre , Chennai (2001) Trends in the prevalence and incidence of tuberculosis in South India. International Journal of Tuberculosis and Lung Disease, 5 (2). pp. 142-157. ISSN Print: 1027-3719; Online: 1815-7920

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Abstract

OBJECTIVE: To study trends in the prevalence and incidence of tuberculosis in south India. METHODS: In 1968–1970, about 100 000 subjects were surveyed for tuberculosis and followed thereafter for 15 years, mainly by repeat survey once every 2.5 years. New entrants were inducted at every repeat survey. Radiographic examination of subjects aged 5 years or more and sputum smear and culture examinations of those with an abnormal shadow were undertaken; tuberculin tests were done initially on all, and at 4, 10 and 15 years in selected samples of those aged 1–9 years. RESULTS: The prevalence of culture-positive tuberculosis decreased by 1.4% per annum to 694/100 000, while that of smear-positive tuberculosis showed no significant decrease from 457/100 000. The annual incidence of culture-positive tuberculosis decreased by 4.3%/annum to 189/100 000 and that of smear-positive tuberculosis decreased by 2.3%/annum to 113/100 000. Decreases in incidence occurred exclusively in those with abnormal radiographic findings suggestive of tuberculosis at the start of the period. The annual risk of tuberculosis infection (ARTI) was initially 2%, and showed no sign of decline over the period. CONCLUSION: The prevalence of tuberculosis and ARTI showed little or no decrease over the 15-year period. A significant decrease in incidence occurred, but exclusively in those with abnormal radiograph suggestive of tuberculosis at the start of the period.

Item Type: Article
Additional Information: Study Paper
Uncontrolled Keywords: tuberculosis; south India; epidemiological trends; prevalence and incidence; disease and infection
Subjects: Tuberculosis > Clinical Research
Divisions: Clinical Research
Depositing User: Rathinasabapati R
Date Deposited: 07 Nov 2013 09:50
Last Modified: 10 Mar 2016 07:14
URI: http://eprints.nirt.res.in/id/eprint/549

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