Rifampicin-induced renal toxicity during retreatment of patients with pulmonary tuberculosis

Banu Rekha, V V and Santha, T and Jawahar, M S (2005) Rifampicin-induced renal toxicity during retreatment of patients with pulmonary tuberculosis. Journal of the Associations of Physicians of India, 53 (Sep). pp. 811-813. ISSN 0004-5772

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Abstract

Rifampicin is a crucial component of treatment regimens for tuberculosis and has been in use since the early 1970’s. It is usually considered safe. Rarely life-threatening complications like acute renal failure or acute thrombocytopaenia may manifest during treatment with rifampicin. In our experience at the Tuberculosis Research Centre of treating more than 8000 pulmonary and extrapulmonary tuberculosis patients with rifampicin-containing regimens over the last 30 years, we are reporting 3 cases of probably rifampicininduced acute renal failure. Despite extreme therapeutic safety of this drug the clinician must be aware of this rare complication, which if detected early is completely reversible.

Item Type:	Article
Subjects:	Tuberculosis > Clinical Research
Divisions:	Clinical Research
Depositing User:	Dr. Rathinasabapati R
Date Deposited:	25 Nov 2013 08:52
Last Modified:	09 Mar 2016 07:00
URI:	http://eprints.nirt.res.in/id/eprint/684

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