Rapid decline in prevalence of pulmonary tuberculosis after DOTS implementation in a rural area of South India

Subramani, R and Radhakrishna, S and Frieden, T R and Kolappan, C and Gopi, P G and Santha, T and Wares, F and Selvakumar, N and Narayanan, P R (2008) Rapid decline in prevalence of pulmonary tuberculosis after DOTS implementation in a rural area of South India. International Journal of Tuberculosis and Lung Disease, 12 (8). pp. 916-920. ISSN Print: 1027-3719; Online: 1815-7920

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Abstract

SETTING: Tiruvallur District in Tamilnadu, South India, where the World Health Organization-recommended DOTS strategy was implemented as a tuberculosis (TB) control measure in 1999. OBJECTIVE: To assess the epidemiological impact of the DOTS strategy on the prevalence of pulmonary tuberculosis (PTB). DESIGN: Surveys of PTB were undertaken on representative population samples aged ⩾15 years (n = 83 000– 90 000), before and at 2.5 and 5 years after the implementation of the DOTS strategy. The prevalence of PTB (smear-positive/culture-positive) was estimated. RESULTS: TB prevalence declined by about 50% in 5 years, from 609 to 311 per 100 000 population for culture-positive TB and from 326 to 169/100 000 for smear-positive TB. The annual rate of decline was 12.6% (95%CI 11.2–14.0) for culture-positive TB and 12.3% (95%CI 8.6–15.8) for smear-positive TB. The decline was similar at all ages and for both sexes. CONCLUSION: With an effi cient case detection programme and the DOTS strategy, it is feasible to bring about a substantial reduction in the burden of TB in the community.

Item Type:	Article
Uncontrolled Keywords:	prevalence; community survey; tuberculosis; DOTS; epidemiology
Subjects:	Tuberculosis > Epidemiological Research Tuberculosis
Depositing User:	Dr. Rathinasabapati R
Date Deposited:	26 Jul 2017 10:05
Last Modified:	26 Jul 2017 10:05
URI:	http://eprints.nirt.res.in/id/eprint/900

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