Methods for the estimation of pyrazinamide and pyrazinoic acid in body fluids

Gurumurthy, Prema and Nair, N G K and Raghupati Sarma, G (1980) Methods for the estimation of pyrazinamide and pyrazinoic acid in body fluids. Indian Journal of Medical Research, 71 (1). pp. 129-134. ISSN 0971-5916

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Abstract

zinoic acid in urine using an anion-exchange resin (Dowex-1) have been described. Recoveries were quantitative, and the sensitivity was 5 μg/ml for ail 3 estimations. In serum, pyrazinoic acid at a concentration of 50 μg/ml did not interfere with the estimation of pyrazinamide. In urine, pyrazinamide and pyrazinoic acid could be separated from each other and estimated even when the 2 compounds were present together at concentrations of 2000 μg/ml each.

Item Type: Article
Subjects: Tuberculosis > Laboratory Research > Biochemical
Divisions: Basic Science Research
Depositing User: Dr. Rathinasabapati R
Date Deposited: 29 Jul 2013 10:29
Last Modified: 11 Mar 2016 10:15
URI: http://eprints.nirt.res.in/id/eprint/145

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