Raghupati Sarma, G and Kannapiran, M and Narayana, A S L and Radhakrishna, S (1978) A qualitative test for the determination of isoniazid acetylator phenotype. Indian Journal of Medical Research, 68 (8). pp. 335-340. ISSN 0971-5916
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Abstract
A qualitative test procedure for phenotyping isoniazid acetylators is described. It is based on a colour reaction which depends on the free sulphadimidine content in the total urine excreted over any one-hour period between 21 and 26 hours following a dose of sulphadimidine 1.0 or 1.5 g. depending on body-weight. The test correctly classified 96 per cent of 109 slow and 96 per cent of 68 rapid inactivators. Storage of urine samples at room-temperature up to 14 days did not affect the accuracy of the results.
Item Type: | Article |
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Subjects: | Tuberculosis > Laboratory Research |
Divisions: | Basic Science Research |
Depositing User: | Dr. Rathinasabapati R |
Date Deposited: | 25 Jul 2013 09:03 |
Last Modified: | 10 Mar 2016 05:09 |
URI: | http://eprints.nirt.res.in/id/eprint/133 |
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