An economic evaluation of implementing a decentralized dengue screening intervention under the National Vector Borne Disease Control Programme in Tamil Nadu, South India.

Muniyandi, Malaisamy and Karikalan, Nagarajan and Ravi, Karunya and Sengodan, Senthilkumar and Krishnan, Rajendran and Tyagi, Kirti and Rajsekar, Kavitha and Raju, Sivadhas and Selvavinayagam, T S (2021) An economic evaluation of implementing a decentralized dengue screening intervention under the National Vector Borne Disease Control Programme in Tamil Nadu, South India. International health, 14 (3). pp. 295-308. ISSN 1876-3405

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Abstract

BACKGROUND Lack of effective early screening is a major obstacle for reducing the fatality rate and disease burden of dengue. In light of this, the government of Tamil Nadu has adopted a decentralized dengue screening strategy at the primary healthcare (PHC) facilities using blood platelet count. Our objective was to determine the cost-effectiveness of a decentralized screening strategy for dengue at PHC facilities compared with the current strategy at the tertiary health facility (THC) level. METHODS Decision tree analysis followed a hypothetical cohort of 1000 suspected dengue cases entering the model. The cost-effectiveness analysis was performed at a 3% discount rate for the proposed and current strategy. The outcomes are expressed in incremental cost-effectiveness ratios (ICERs) per quality-adjusted life years gained. One-way sensitivity analysis and probabilistic sensitivity analysis were done to check the uncertainty in the outcome. RESULTS The proposed strategy was found to be cost-saving and ICER was estimated to be -41 197. PSA showed that the proposed strategy had a 0.84 probability of being an economically dominant strategy. CONCLUSIONS The proposed strategy is cost-saving, however, it is recommended to consider optimal population coverage, costs to economic human resources and collateral benefits of equipment.

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
Uncontrolled Keywords:	cost-effectiveness, dengue, economic evaluation, QALY, screening
Subjects:	Tuberculosis > Economical Research
Divisions:	Statistics
Depositing User:	Dr. Rathinasabapati R
Date Deposited:	29 Nov 2022 06:56
Last Modified:	28 Mar 2023 07:24
URI:	http://eprints.nirt.res.in/id/eprint/1852

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