The Cost-Effectiveness of the BEAT-TB Regimen for Pre-Extensively Drug-Resistant TB

Malaisamy, Muniyandi and Ramesh, PM and Wells, WA and Alavadi, Umesh (2023) The Cost-Effectiveness of the BEAT-TB Regimen for Pre-Extensively Drug-Resistant TB. The Cost-Effectiveness of the BEAT-TB Regimen for Pre-Extensively Drug-Resistant TB, 8 (411). pp. 1-10.

Text The Cost-Effectiveness of the BEAT-TB Regimen for.pdf - Published Version Download (418kB)

Abstract

Objective: To measure the economic impacts of the longer pre-XDR-TB treatment regimen and the shorter BEAT-TB India regimen. Methods: In the current study, the economic impacts of the current 18-month pre-XDR-TB treatment regimen and the 6–9 month BEAT-TB regimen were evaluated using an economic model via a decision tree analysis from a societal perspective. The incremental costs and quality-adjusted life years (QALYs) gained from the introduction of the BEAT- TB regimen for pre-XDR-TB patients were estimated. Results: For a cohort of 1000 pre-XDR-TB patients, we found that the BEAT-TB India regimen yielded higher undiscounted life years (40,548 vs.21,009) and more QALYs gained (27,633 vs. 15,812) than the 18-month regimen. The BEAT-TB India regimen was found to be cost-saving, with an incremental cost of USD −128,651 when compared to the 18-month regimen. The current analysis did not consider the possibility of reduced TB recurrence after use of the BEAT-TB regimen, so it might have under-estimated the benefits. Conclusion: As a lower-cost intervention with improved health outcomes, the BEAT-TB India regimen is dominant when compared to the 18-month regimen.

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
Uncontrolled Keywords:	uberculosis; infectious diseases; economic impact; pre-XDR-TB treatment regimen;shorter BEAT-TB India regimen; societal perspective; cost-effective BEAT-TB regimen
Subjects:	Tuberculosis > Economical Research
Divisions:	Health Economics
Depositing User:	Mrs. N Lakshmi
Date Deposited:	24 Aug 2023 11:00
Last Modified:	09 Feb 2024 11:06
URI:	http://eprints.nirt.res.in/id/eprint/1972

Actions (login required)

View Item