Evaluating the cost-effectiveness of Cy-Tb for LTBI in India: a comprehensive economic modelling analysis

Malaisamy, Muniyandi and Nagarajan, Karikalan and Mathiyazhagan, Kavi and Tyagi, Kirti and Rajsekar, Kavitha and Chandrasekaran, Padmapriyadarsini (2025) Evaluating the cost-effectiveness of Cy-Tb for LTBI in India: a comprehensive economic modelling analysis. Evaluating the cost-effectiveness of Cy-Tb for LTBI in India: a comprehensive economic modelling analysis, 17 (3). pp. 259-269.

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Abstract

Latent tuberculosis infection (LTBI) remains a significant challenge, as there is no gold standard diagnostic test. Current methods used for identifying LTBI are the interferon- γ release assay (IGRA), which is based on a blood test, and the tuberculin skin test (TST), which has low sensitivity. Both these tests are inad- equate, primarily because they have limitations with the low bacterial burden characteristic of LTBI. This high- lights the need for the development and adoption of more specific and accurate diagnostic tests to effectively identify LTBI. Herein we estimate the cost-effectiveness of the Cy-Tb test as compared with the TST for LTBI diagnosis.

Affiliation: ICMR-National Institute for Research in Tubercuosis
Item Type: Article
URI: http://eprints.nirt.res.in/id/eprint/2085

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