QuantiFERON Supernatant-Based Host Biomarkers Predicting Progression to Active Tuberculosis Disease Among Household Contacts of Tuberculosis Patients

Daniel, EA and Thiruvengadam, K and Rajamanickam, A and Chandrasekaran, P and Pattabiraman, S and Bhanu, B and Shivakumar, SVBY and Babu, S and Hanna, LE (2023) QuantiFERON Supernatant-Based Host Biomarkers Predicting Progression to Active Tuberculosis Disease Among Household Contacts of Tuberculosis Patients. QuantiFERON Supernatant-Based Host Biomarkers Predicting Progression to Active Tuberculosis Disease Among Household Contacts of Tuberculosis Patients, 76(10) (180213).

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Abstract

The positive predictive value of tuberculin skin test and current generation interferon gamma release assays are very low leading to high numbers needed to treat. Therefore, it is critical to identify new biomarkers with high predictive accuracy to identify individuals bearing high risk of progression to active tuberculosis (TB).

Affiliation: ICMR-National Institute for Research in Tuberculosis
Item Type: Article
URI: http://eprints.nirt.res.in/id/eprint/2226

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