Effect of diethylcarbamazine on the alveolitis of tropical eosinophilia

Vijayan, V K and Sankaran, K and Venkatesan, P and Prabhakar, R (1991) Effect of diethylcarbamazine on the alveolitis of tropical eosinophilia. Respiration , 58 (5-6). pp. 255-259. ISSN Print: 0025-7931; Online: 1423-0356

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Abstract

Bronchoalveolar lavage studies in 33 patients with acute untreated tropical eosinophilia have demonstrated intense eosinophilic alveolitis. Following treatment with a standard 3-week course of diethylcarbamazine, there was a significant fall in lung eosinophils (p <0.001). However; a mild alveolitis characterised by hypercellular lavage fluid due to a significant increase in absolute alveolar macrophages (p < 0.001) and due to an increase in both the absolute number (p <0.01) and percentage of eosinophils (p = 0.02) was persisting at 1 month despite treatment. Long-term follow-up is essential to know the fate of alveolitis.

Item Type: Article
URI: http://eprints.nirt.res.in/id/eprint/310

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