Monocyte Antimycobacterial Activity before and after Mycobacterium bovis BCG Vaccination in Chingleput, India, and London, United Kingdom

Cheng, S H and Walker, K B and Lowrie, D B and Mitchison, D A and Swamy, R and Datta, M and Prabhakar, R (1993) Monocyte Antimycobacterial Activity before and after Mycobacterium bovis BCG Vaccination in Chingleput, India, and London, United Kingdom. Infection and Immunity, 61 (10). pp. 4501-4503. ISSN Print: 0019-9567; Online: 1098-5522

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Abstract

Monocytes from purified protein derivative S hIantous-negative children and young’ adults inhibited. intracellular growth of Mycobacterium microti more in Chingleput than in London. Mycobacterium bovis BCG vaccination did not enhance bacteriostasis with the Indians but did so with the Londoners. No evidence was found for involvement of cytokines such as macrophage-activating factor and granulocyte macrophage colony-stimulating factor in the differences.

Item Type: Article
URI: http://eprints.nirt.res.in/id/eprint/335

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