Pyrazinamide deamidase activity in tuberculous disease
Gurumurthy, Prema and Krishnamurthy, P V and Raghupati Sarma, G (1981) Pyrazinamide deamidase activity in tuberculous disease. American Review of Respiratory Diseases, 124 (1). p. 97. ISSN 0003-0805
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Official URL: http://www.atsjournals.org/loi/ajrccm/
Abstract
To investigate whether pyrazinamide deamidase activity is suppressed in tuberculosls, serial serum concentrations of pyrazinamide, following 40 mg of pyrazinamide per kg, were determined in 10 patients with-sputum positive pulmonary tuberculosis and in 10 control subjects without disease. The concentrations and the half-lives of pyrazinamide were similar in the 2 groups, suggesting no suppression of the deamidase activity in tuberculous patients.
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Item Type: | Article | ||
Subjects: | Tuberculosis > Laboratory Research > Biochemical,Clinical and Pharmacological | ||
Divisions: | Basic Science Research > Biochemistry and Pharmacology | ||
Depositing User: | Dr. Rathinasabapati R | ||
Date Deposited: | 31 Jul 2013 06:50 | ||
Last Modified: | 14 Mar 2016 08:53 | ||
URI: | http://eprints.nirt.res.in/id/eprint/153 |
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