Evaluation of ELISA as a diagnostic test in pulmonary tuberculosis

Narayanan, P R and Acharyulu, G S and Krishnamurthy, P V and Ravoof, Abdul and Tripathy, S P (1983) Evaluation of ELISA as a diagnostic test in pulmonary tuberculosis. Indian Journal of Tuberculosis, 30 (1). pp. 29-32. ISSN 0019-5705

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The reproducibility and ability of ELISA to discriminate patients with active disease from those infected were investigated.. The results obtained on 60 sputum-positive adult tuberculous patients and 60 adult control subjects showed groupwise discrimination. The anti-PPD antibodies (Ig G class) were significantly elevated in tuberculous patients as compared with control subjects. But because of the large day-to-day variation and considerable overlap in the distribution of antibody levels in tuberculous and control subjects, it is not possible to use ELISA as a diagnostic tool for adult pulmonary tuberculosis.

Item Type: Article
Subjects: Tuberculosis > Laboratory Research > Immunological
Divisions: Basic Science Research > Immunology
Depositing User: Dr. Rathinasabapati R
Date Deposited: 06 Aug 2013 09:43
Last Modified: 16 Mar 2016 05:22
URI: http://eprints.nirt.res.in/id/eprint/162

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