Assay of ethambutol in pharmaceutical preparations

Gurumurthy, Prema and Narayana, A S L and Raghupati Sarma, G and Somasundaram, P R (1984) Assay of ethambutol in pharmaceutical preparations. Lung India, 2 (1). pp. 143-145. ISSN Print: 0970-2113; Online: 0974-598X

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Ethambutol tablets of 200 and 400 mg denominations were assayed by the standard non-aqueous titration method and a simpler calorimetric method. With the titrimetric method, assay values, appreciably higher than the stated content (117% or more), were obtained with the products of 4 companies, while all the values were within 6% of the stated content by the calorimetric method. Rifampicin and pyrazinamide interfered with the estimation of ethambutol by both methods: isoniazid, however, caused an overestimation with the titrimetric method only.

Item Type: Article
Subjects: Tuberculosis > Laboratory Research > Biochemical
Divisions: Basic Science Research > Biochemistry
Depositing User: Dr. Rathinasabapati R
Date Deposited: 07 Aug 2013 08:31
Last Modified: 17 Mar 2016 09:05

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