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Surface markers of lymphoblasts in acute lymphoblastic leukaemia

Rajajee, S and Pushpa, V and Narayanan, P R (1984) Surface markers of lymphoblasts in acute lymphoblastic leukaemia. Indian Journal of Haematology, 2 (4). pp. 234-235. ISSN Print: 0971-4502 ; Online: 0974-0449

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Official URL: http://www.ncbi.nlm.nih.gov/pmc/journals/1357/

Abstract

58 children with acute lymphoblastic leukaemia (ALL) were studied for the effect of initial clinical and laboratory features and surface markers of lymphoblasts on the prognosis. 18.9% of them had T cell leukaemia while 3.4% had B-cell leukaemia. Six pre-treatment features were related to T-cell ALL, i.e. - age over 6 years, boys, presence of mediastinal enlargement, haemoglobin over 8g/dl, markedly elevated leucocyte count and CNS involvement. 90% of T-Cell ALL survived for less than 6 months. Both the cases of B-cell leukaemia died within 8 weeks. Identification of T and B cell leukaemia warrants more aggressive treatment for these patients to achieve remission and survive longer.

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Item Type: Article
Subjects: Tuberculosis > Laboratory Research > Immunological
Tuberculosis > Clinical Research
Divisions: Clinical Research
Depositing User: Dr. Rathinasabapati R
Date Deposited: 07 Aug 2013 09:51
Last Modified: 17 Mar 2016 09:08
URI: http://eprints.nirt.res.in/id/eprint/177

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