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Cell mediated immunity in post-streptococcal glomerulonephritis

Rajajee, S and Narayanan, P R and Moses, S G P and Sundaravalli, N (1984) Cell mediated immunity in post-streptococcal glomerulonephritis. Indian Pediatrics, 21 (8). pp. 615-621. ISSN Print: 0019-6061; Online:0974-7559

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Abstract

Cell mediated immunity was assessed in 30 children with acute post streptococcal glomerulonephritis (APSGN) in parallel with 20 normal children and 15 children without nephritis who showed evidence of skin-sore ß-Hemolytic streptococcal infection. Delayed cutaneous hypersensitivity to 2,4, dinitrochloro benzene (DNCB) was similar in the three groups. There were no significant differences in the proportion of early and total T-rosettes. Lymphocyte transformation response to phytohemagglutinin- P (PHA), purified protein derivative (PPD) and BCG was similar in them, indirect leucocyte migration inhibition response to PPD, streptokinase streptodornase (SK-SD), and group A ß-Hemolytic T12 streptococcal antigens were not significantly different in patients when compared to normal controls and streptococcal infection controls. Cell mediated immunity was normal in APSGN in children by all the parameters studied.

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Item Type: Article
Uncontrolled Keywords: Cell mediated immunity, Acute poststreptococcal glomerulonephritis
Subjects: Tuberculosis > Laboratory Research > Immunological
Tuberculosis > Clinical Research
Tuberculosis > Epidemiological Research
Divisions: Clinical Research
Depositing User: Dr. Rathinasabapati R
Date Deposited: 07 Aug 2013 10:06
Last Modified: 17 Mar 2016 09:07
URI: http://eprints.nirt.res.in/id/eprint/178

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