Pharmacokinetics of anti-TB drugs in children and adolescents with drug-resistant TB: a multicentre observational study from India

Agibothu Kupparam, Hemanth Kumar and Shah, Ira and Chandrasekaran, Padmapriyadarshini and Mane, Sushant and Sharma, Sangeeta and Thangavelu, Bharathi Raja and Vilvamani, Sudha and Annavi, Vijayakumar and Mahalingam, Santhana Mahalingam and Thiruvengadam, Kannan and Navaneethapandian, Poorana Ganga Devi and Gandhi, Srushti and Poojari, Vishrutha and Nalwalla, Zahabiya and Oswal, Vikas and Giridharan, Prathiksha and Babu, Sarath Balaji and Rathinam, Sridhar and Frederick, Asha and Mankar, Suhbangi and Shanmugam Murugaiha, Jeyakumar (2024) Pharmacokinetics of anti-TB drugs in children and adolescents with drug-resistant TB: a multicentre observational study from India. Pharmacokinetics of anti-TB drugs in children and adolescents with drug-resistant TB: a multicentre observational study from India, 79 (2939). pp. 2939-2947.

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Abstract

Drug-resistant tuberculosis (DR-TB) is one of the challenging forms of TB to treat, not only in adults but also in children and adolescents. Further, there is a void in the treatment strategy exclusively for children due to various reasons, including paucity of pharmacokinetic (PK) data on anti-TB drugs across the globe. In this context, the present study aimed at assessing the PK of some of the anti-TB drugs used in DR-TB treatment regimens.

Affiliation:	ICMR-National Institute for Research in Tuberculosis
Item Type:	Article
Uncontrolled Keywords:	Pharmacokinetics, Drug-resistant tuberculosis, plasma concentrations, multicentre observational, Plasma drug measurement
Subjects:	Tuberculosis > Laboratory Research Tuberculosis Tuberculosis > Laboratory Research > Pharmacological
Divisions:	Basic Science Research > Clinical Pharmacology
Depositing User:	Mrs. N Lakshmi
Date Deposited:	16 Apr 2025 10:29
Last Modified:	16 Apr 2025 10:29
URI:	http://eprints.nirt.res.in/id/eprint/2034

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