Short course chemotherapy in the treatment of brain tuberculoma - a controlled clinical trial

Ramachandran, Rajeswari and Kalyanaraman, S (1989) Short course chemotherapy in the treatment of brain tuberculoma - a controlled clinical trial. Neurology India, 37. p. 512. ISSN Print: 0028-3886; Online:1998-4022

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Abstract

74 cases diagnosed to have brain tuberculoma on the basis of clinical and CT Scan criteria have been admitted to study in a 24 month period from October, 1986. These cases were randomly allocated to either Rif+INH+Pyrazinamide given daily or thrice weekly for 3 months followed by Rif and INH twice-weekly for a period of 6 months. therapy and The efficacy of short course chemothe serial CT Scan changes in relation to therapy are being evaluated in this prospective study. A biopsy is done after 2 months of treatment if the scan does not show 20% reduction in size of the mass.

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