Venkatesan, P and Somasundaram, P R
(1989)
A probabilistic approach for modelling the joint action of drugs.
Biomedicine, 9 (1).
pp. 13-18.
ISSN 0970 2067
Abstract
An understanding of the joint action of drugs is
becoming increasingly important in a variety of scientific
disciplines, ranging from pharmacology and toxicology on the
one hand to industrial hygiene and environmental protection on
the other. The action of even a single drug upon a biological
organism involves a complex sequence of processes and if
more than one drug is present, the situation is further complicated
The role of mathematical models in this context is
now widely recognized (Plackett & Hewlett 1952, Hewlett and
Plackett, 1959, 1979, Ashford and Cobby 1974, Ashford 7981)
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