Fully intermittent six month regimens for pulmonary tuberculosis in South India.

Balasubramanian, Rani (1991) Fully intermittent six month regimens for pulmonary tuberculosis in South India. Indian Journal of Tuberculosis, 38 (2). pp. 51-53. ISSN 0019-5705

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Abstract

A large-scale multi-centric study in South India was organised by the Tuberculosis Research Centre, Madras. The regimens c o n s i s t e d o f Rifampicin, Isoniazid, Streptomycin and Pyrazinamide, administered under supervision, twice or thrice a week for the first 2 months, followed by different combinations of 2 or 3 drugs administered twice or once a week for the next 4 months. The patients were followed up with intensive bacteriological examination. The response at the end of chemotherapy and the relapse rates during a 4½-year follow-up in approximately 1,000 patients with drug-sensitive organisms initially and 200 patients with organisms initially drug resistant are presented.

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