Suhadev, M and Ganapathy, S and Sivasubramanian, S and Santha Devi, T
(1995)
A retrospective study of 'non-compliant' patients in controlled clinical trials of short course chemotherapy.
Indian Journal of Tuberculosis, 42 (4).
pp. 221-224.
ISSN 0019-5705
Abstract
In a total of 2,332 pulmonary
short-course chemotherapy studies conducted
during 1975-1985, there were 60 ‘noncompliant’
patients who had received less
than 75% of the prescribed treatment. A
retrospective study was undertaken to find
out the reasons for default in these patients
since the Tuberculosis Research Centre has
very stringent criteria of selection of patients
for their, studies, an adequate system. of
motivation of the patients and well organised
infrastructure for retrieval of the defaulters.
Unwillingness for treatment was stated
as the reason for default by 20 patients and
adverse reactions to the drugs by 16 patients.
Other major reasons given were pressure of
work (14 patients), frequent outstation visits
(13) and migration (12).
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