Mycobacterium nature of human monocytes in vitro

Viswanath, V and Narayanan, P R (1996) Mycobacterium nature of human monocytes in vitro. Current Science, 70 (11). pp. 970-975. ISSN 0011-3891

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Protective immunity in tuberculosis is attributed to destruction and elimination of the pathogen M. tuberculosis by activated macrophages. Activation of macrophages is brought about by the lymphokines released by antigen sensitized T lymphocytes. In the past ten years several review articles and research papers have been published on the antimycobacterial activity of macrophages. However convincing evidence of intra-cellular killing of M. tuberculosis was lacking in most of these experiments. An in vitro experiment wherein we are able to demonstrate mycobactericidal activity by monocytes could yield valuable information in understanding of tuberculoimmunity and also to resolve immunomodulating agents as an adjunct to chemotherapy.

Item Type: Article
Subjects: Tuberculosis > Laboratory Research > Immunological
Divisions: Basic Science Research > Immunology
Depositing User: Dr. Rathinasabapati R
Date Deposited: 27 Sep 2013 11:39
Last Modified: 14 Mar 2016 05:14

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