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Non-HLA gene polymorphism in pulmonary tuberculosis

Selvaraj, P and Hill, A V S and Narayanan, P R and Reetha, A M and Colston, M J (1998) Non-HLA gene polymorphism in pulmonary tuberculosis. In: Workshop on Tuberculosis Research : in to the 21st Century, 1998.

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Abstract

BCG vaccination has been shown to give protection against tuberculosis. However, South Indian (Chingleput) Trial of BCG vaccination did not give any protection against bacillary forms of tuberculosis. A number of hypotheses and possibilities were put forward for this failure (1). One of the possibilities suggested was the genetics of the people (Host genetics) living in that region. Pulmonary tuberculosis is a granulomatous lung disease caused by Mycobactrium tuberculosis. Susceptibility to tuberculosis has been suggested to be multifactorial. Though environmental and socio-economic factors are primarily related, numerous studies have emphasised the importance of host resistance and hereditary susceptibility (2,3).

NIRT Creators:
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Item Type: Conference or Workshop Item (Paper)
Additional Information: RP199821
Subjects: Tuberculosis > Laboratory Research > Immunological
Divisions: Basic Science Research > Immunology
Depositing User: Dr. Rathinasabapati R
Date Deposited: 30 Oct 2013 07:08
Last Modified: 14 Mar 2016 04:34
URI: http://eprints.nirt.res.in/id/eprint/476

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