Studies on sister chromatid exchanges in peripheral lymphocytes of spray painters

Gajalakshmi, P and Mallick, P and Venkatesan, P and Santhiya, S T and Ramesh, A (2002) Studies on sister chromatid exchanges in peripheral lymphocytes of spray painters. Journal of Environmental Pathology, Toxicology and Oncology, 21 (1). pp. 63-65. ISSN Print: 0731-8898; Online: 2162-6537

[thumbnail of 200207.pdf] PDF
200207.pdf - Published Version
Restricted to Registered users only

Download (84kB) | Request a copy


In a comparative study of sister chromatid exchanges (SCEs) in cultured lymphocytes, we evaluated the genotoxic risk in 104 male spray painters employed in repair workshops in Chennai City, India, and 50 matched healthy, unexposed controls. We found a higher frequency of SCEs among painters (3.74 ± 0.11, x ± SE) than among controls (2.15 ± 0.08), and among smoking painters (4.03 ± 0.21) than among nonsmokng painters (3.55 ± 0.13), with no significant difference in controls (smokers: 2.1 ± 0.2; nonsmokers: 2.2 .1). Alcoholism did not contribute to an increased SCE frequency. Stepwise multiple linear regression analysis on painters showed that duration of service, smoking, and alcoholism significantly affected SCE scores and explained the 14% variation observed.

Item Type: Article
Uncontrolled Keywords: sister chromatid exchanges (SCEs), spray painters, genotoxicity, occupational exposure
Subjects: Tuberculosis > Laboratory Research > Pathological
Tuberculosis > Epidemiological Research
Divisions: Basic Science Research
Depositing User: Dr. Rathinasabapati R
Date Deposited: 08 Nov 2013 06:06
Last Modified: 10 Mar 2016 04:31

Actions (login required)

View Item View Item