Method for the estimation of acetylisoniazid in urine

Venkataraman, P and Eidus, L and Tripathy, S P (1968) Method for the estimation of acetylisoniazid in urine. Tubercle, 49 (2). pp. 210-216. ISSN 0041-3879

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A method for the estimation of acetylisoniazid in urine is described. It is simple, sensitive and reliable and follows Beer’s law between 10 μg./ml. and 40 μg./ml. It yields complete recovery of acetylisoniazid from specimens of urine to which the compound has been added in known concentrations. In this procedure, the drug-containing urine itself serves as the blank if the reagents are mixed first and then the urine added. Isoniazid in high concentrations produces a colour reaction in this method. This interference is eliminated by potassium permanganate which destroys isoniazid but not acetylisoniazid under the conditions of the estimation.

Item Type: Article
Subjects: Tuberculosis > Laboratory Research > Bacteriological
Divisions: Basic Science Research
Depositing User: Dr. Rathinasabapati R
Date Deposited: 19 Jul 2013 05:40
Last Modified: 08 Mar 2016 06:26

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