Promoting Open Access to Exploring the Research

A qualitative test for the determination of isoniazid acetylator phenotype

Raghupati Sarma, G and Kannapiran, M and Narayana, A S L and Radhakrishna, S (1978) A qualitative test for the determination of isoniazid acetylator phenotype. Indian Journal of Medical Research, 68 (8). pp. 335-340. ISSN 0971-5916

[img]
Preview
PDF
197801.pdf - Published Version

Download (32kB)
Official URL: http://www.icmr.nic.in/Publications/IJMR.html

Abstract

A qualitative test procedure for phenotyping isoniazid acetylators is described. It is based on a colour reaction which depends on the free sulphadimidine content in the total urine excreted over any one-hour period between 21 and 26 hours following a dose of sulphadimidine 1.0 or 1.5 g. depending on body-weight. The test correctly classified 96 per cent of 109 slow and 96 per cent of 68 rapid inactivators. Storage of urine samples at room-temperature up to 14 days did not affect the accuracy of the results.

Item Type: Article
Subjects: Tuberculosis > Laboratory Research
Divisions: Basic Science Research
Depositing User: Dr. Rathinasabapati R
Date Deposited: 25 Jul 2013 09:03
Last Modified: 10 Mar 2016 05:09
URI: http://eprints.nirt.res.in/id/eprint/133

Actions (login required)

View Item View Item